Genetic Evidence of Dobrava Virus in Apodemus agrarius in Hungary
Author Information
Author(s): Jerrold J. Scharninghausen, Hermann Meyer, Martin Pfeffer, Donald S. Davis, Rodney L. Honeycutt
Primary Institution: Texas A&M University
Hypothesis
The study evaluates the distribution of hantaviruses in related rodent hosts.
Conclusion
Dobrava virus was isolated from Apodemus agrarius in Hungary, suggesting potential host switching.
Supporting Evidence
- Dobrava virus was isolated from Apodemus agrarius in Hungary.
- The samples isolated group with DOB samples previously isolated from A. flavicollis.
- Phylogenetic analysis indicates a closer relationship between A. agrarius DOB from Hungary and A. flavicollis DOB.
- Evidence of host switching was observed between A. agrarius and A. flavicollis.
Takeaway
Scientists found a virus in a type of mouse in Hungary, which might mean that the virus can jump between different types of mice.
Methodology
Rodents were live-trapped, euthanized, and their tissues were analyzed using nested polymerase chain reaction.
Limitations
The sequence data are limited and may not represent the full diversity of hantaviruses.
Participant Demographics
Rodents collected from Tazar Air Force Base in eastern Hungary.
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