ROS-Mediated Signalling in Bacteria: Zinc-Containing Cys-X-X-Cys Redox Centres and Iron-Based Oxidative Stress
2012
ROS-Mediated Signalling in Bacteria: Zinc-Containing Cys-X-X-Cys Redox Centres and Iron-Based Oxidative Stress
publication
Evidence: moderate
Author Information
Author(s): Dário Ortiz de Orué Lucana, Wedderhoff Ina, Groves Matthew R.
Primary Institution: University of Osnabrueck
Conclusion
Bacteria use redox-sensitive proteins to detect and respond to oxidative stress caused by reactive oxygen species.
Supporting Evidence
- Bacteria are constantly exposed to reactive oxygen species that can cause damage.
- Zinc plays a crucial role in stabilizing proteins and protecting them from oxidative stress.
- Redox-sensitive proteins can undergo structural changes in response to oxidative stress.
Takeaway
Bacteria can sense harmful molecules called reactive oxygen species and use special proteins to protect themselves and stay healthy.
Methodology
The review analyzes molecular mechanisms involved in sensing and response to oxidative stress using various biological tools.
Digital Object Identifier (DOI)
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