Reference Intervals for Cord Blood Minerals in Preterm Infants
Author Information
Author(s): Tanis R. Fenton, Andrew W. Lyon, Sarah M. Rose
Primary Institution: University of Calgary
Hypothesis
The study aims to determine how gestational age and maternal/neonatal variables influence reference intervals for cord blood bone minerals in preterm infants.
Conclusion
Gestational age and certain maternal and neonatal factors should be considered when developing reference intervals for preterm infants' cord blood minerals.
Supporting Evidence
- Calcium levels in cord blood increase with gestational age.
- Phosphate and magnesium levels in cord blood decrease with gestational age.
- Certain maternal conditions like pregnancy-induced hypertension affect mineral levels.
Takeaway
This study looked at the levels of important minerals in the blood of premature babies and found that these levels change as babies grow older in the womb.
Methodology
A cross-sectional study analyzing cord blood serum from preterm infants using multiple linear regression.
Potential Biases
Potential bias due to the exclusion of infants with certain medical conditions.
Limitations
The study was conducted at a single center, which may limit the generalizability of the results.
Participant Demographics
The sample included 506 preterm infants and 54 term infants, with a majority being singleton births.
Statistical Information
P-Value
<0.001
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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