Automated Chemical Synthesis: Batch-Type Reactor Automation and Software Design
Author Information
Author(s): Daniel F. Chodosh, Kenneth Kamholz, Sidney H. Levinson, Robert Rhinesmith
Primary Institution: Smith Kline & French Laboratories
Hypothesis
The application of automation technology at earlier stages of research and development can optimize synthetic route selection.
Conclusion
The study successfully developed a computer-controlled batch-type chemical reactor that can self-direct experiments and optimize reactions.
Supporting Evidence
- The automated reactor can perform on-line chemical analyses and optimize reactions.
- Temperature control systems were designed to respond quickly to changes during experiments.
- Liquid trafficking systems were developed to ensure accurate delivery of reagents.
Takeaway
This study created a robot that can mix chemicals and run experiments by itself, making it easier and faster to find the best ways to make new medicines.
Methodology
The research involved designing and constructing a computer-controlled batch-type reactor that automates chemical synthesis and analysis.
Limitations
The study primarily focuses on laboratory-scale automation and may not directly translate to larger production scales.
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