Chlorella Supplement Increases Salivary Immunoglobulin A in Humans
Author Information
Author(s): Otsuki Takeshi, Shimizu Kazuhiro, Iemitsu Motoyuki, Kono Ichiro
Primary Institution: University of Tsukuba
Hypothesis
Ingestion of a chlorella-derived multicomponent supplement enhances mucosal immune functions.
Conclusion
Ingestion of a chlorella-derived multicomponent supplement increases salivary SIgA secretion and possibly improves mucosal immune function in humans.
Supporting Evidence
- Salivary SIgA concentrations were significantly elevated after chlorella ingestion compared to baseline.
- No difference was observed in salivary SIgA concentrations before and after placebo ingestion.
- Compliance rates for placebo and chlorella ingestions were high at 97.0% and 95.3%, respectively.
Takeaway
Taking chlorella tablets for four weeks helps your body make more of a special immune protein in your saliva that helps fight germs.
Methodology
Fifteen men took 30 placebo and 30 chlorella tablets per day for 4 weeks, with saliva samples collected before and after each trial.
Potential Biases
Potential bias due to funding from SunChlorella Co., Ltd., which provided the supplements.
Limitations
The study could not investigate eating habits or perform blood chemical analysis, and the clinical significance of changes in salivary SIgA secretion was not established.
Participant Demographics
Fifteen young men, mean age 20.4 years, none with chronic diseases or regular supplement use.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.01
Digital Object Identifier (DOI)
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