PREDICTING THE ONSET OF DEMENTIA WITH LONGITUDINAL OBJECTIVE MEASURES OF PHYSICAL FUNCTION
2024

Predicting Dementia Onset with Physical Function Measures

Sample size: 518 publication Evidence: moderate

Author Information

Author(s): Schaefer Sydney, Peterson Daniel, Bravell Marie Ernsth, Finkel Deborah

Primary Institution: Arizona State University

Hypothesis

Does the decline in physical function accelerate before the onset of dementia?

Conclusion

The study found that fine motor skills decline faster in individuals who will develop dementia, suggesting they may be an early indicator of risk.

Supporting Evidence

  • Fine motor skills declined faster in the dementia onset group, with differences emerging 9 years prior to dementia onset.
  • Gait and grip strength showed no differences in the rate of change between groups.
  • Fine motor decline occurred at the same rate as cognitive decline measured with the Mini-mental status exam.

Takeaway

Older people who will get dementia might start having trouble with tasks like using their hands before they actually show memory problems.

Methodology

The study analyzed changes in physical function measures over up to 26 years in older adults, comparing those who developed dementia with those who did not.

Limitations

The study only included data prior to dementia diagnosis and relied on clinical consensus for dementia diagnosis.

Participant Demographics

The study involved 518 older adults, with 259 diagnosed with dementia.

Digital Object Identifier (DOI)

10.1093/geroni/igae098.4351

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