Heart Rate Recovery and Inflammation in PCOS Patients
Author Information
Author(s): Giallauria Francesco, Orio Francesco, Lombardi Gaetano, Colao Annamaria, Vigorito Carlo, Tafuri Maria Giovanna, Palomba Stefano
Primary Institution: University of Naples 'Federico II'
Hypothesis
This study was designed to study the relationships between heart rate recovery (HRR) and inflammatory markers in PCOS women.
Conclusion
Abnormal HRR and inflammatory markers are closely associated in PCOS women, likely increasing their cardiovascular risk profile.
Supporting Evidence
- 89 out of 243 patients presented abnormal HRR.
- Serum CRP and WBCs concentrations were significantly higher in PCOS patients with abnormal HRR.
- HRR was significantly associated with both CRP and WBCs.
- The group within the highest quartile of CRP was more likely to have abnormal HRR.
Takeaway
Women with polycystic ovary syndrome (PCOS) who have a slow heart rate recovery after exercise also tend to have higher levels of inflammation, which can be bad for their heart health.
Methodology
243 young PCOS patients underwent hormonal and metabolic profiling, white blood cell count, C-reactive protein measurement, and heart rate recovery assessment after exercise.
Potential Biases
Potential confounding factors such as diet status were not controlled.
Limitations
The cross-sectional nature of the study does not allow for causal conclusions.
Participant Demographics
Young women diagnosed with polycystic ovary syndrome.
Statistical Information
P-Value
0.001
Confidence Interval
95% CI 1.07–2.33
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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