Measuring Lens Elasticity in Monkey Eyes
Author Information
Author(s): Noël M. Ziebarth, Ewa P. Wojcikiewicz, Fabrice Manns, Vincent T. Moy, Jean-Marie Parel
Primary Institution: Bascom Palmer Eye Institute, University of Miami
Hypothesis
Can atomic force microscopy (AFM) be used to measure the elasticity of intact crystalline lenses?
Conclusion
AFM can effectively measure the elasticity of the whole lens, and the values obtained are comparable to those from dynamic mechanical analysis on human lenses.
Supporting Evidence
- Young's modulus was measured at 1,720±880 Pa in the lenses.
- The values obtained using AFM are similar to those from dynamic mechanical analysis on human lenses.
- The study demonstrated the feasibility of using AFM for whole lens elasticity measurements.
Takeaway
Scientists used a special tool to measure how stretchy monkey lenses are, and found they are similar to human lenses.
Methodology
AFM measurements were performed on intact lenses from 18 fresh cynomolgus monkey cadaver eyes.
Limitations
The study used cadaver eyes, which may not fully represent living tissue properties.
Participant Demographics
Cynomolgus monkeys aged 4-10 years.
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