Immunosuppression Effects on Salmonella Dublin in Cattle
Author Information
Author(s): Sanne R Lomborg, Jørgen S Agerholm, Asger L Jensen, Liza R Nielsen
Primary Institution: University of Copenhagen
Hypothesis
Does immunosuppression lead to the excretion of Salmonella Dublin in cattle with high antibody levels?
Conclusion
Immunosuppression did not result in the excretion of Salmonella Dublin in milk or faeces from the infected cattle.
Supporting Evidence
- No shedding of Salmonella Dublin was found in faeces or milk during the study.
- Immunosuppression was confirmed by increased leukocyte counts.
- S. Dublin was isolated from tissues of only three out of nine cattle.
Takeaway
The study found that stressed cattle with high antibody levels to Salmonella Dublin did not shed the bacteria, suggesting they might not be as risky as thought.
Methodology
Nine adult cattle were immunosuppressed and monitored for Salmonella Dublin in faeces, milk, and organs over 7-14 days.
Potential Biases
Potential bias in the selection of cattle based on antibody levels.
Limitations
The sample size was small, and the study may not represent all cattle populations.
Participant Demographics
Nine adult Holstein cattle from four dairy herds, aged 1.5 to 6 years.
Digital Object Identifier (DOI)
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