Lyme Neuroborreliosis in HIV-1 Positive Men Treated with Doxycycline
Author Information
Author(s): Daniel Bremell, Christer Säll, Magnus Gisslén, Lars Hagberg
Primary Institution: Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Sweden
Hypothesis
Co-infection with HIV-1 and Lyme neuroborreliosis is more common than previously thought.
Conclusion
The study suggests that co-infection with HIV-1 and Lyme neuroborreliosis is likely more prevalent than previously recognized, especially in immunocompromised patients.
Supporting Evidence
- All four patients were treated with oral doxycycline and showed good clinical outcomes.
- Three patients had subnormal CD4 cell counts indicating impaired immunity.
- The atypical symptoms in immunocompromised patients suggest a need for increased awareness among healthcare providers.
Takeaway
Doctors should check for Lyme disease in HIV patients who have unusual neurological symptoms, as it can happen more often than we thought.
Methodology
Case series of four patients with HIV-1 and Lyme neuroborreliosis treated with oral doxycycline.
Limitations
The study is based on a small sample size and may not represent the broader population.
Participant Demographics
All participants were Caucasian men with varying ages and medical histories.
Digital Object Identifier (DOI)
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