PPARs in Neuroinflammation
2008
PPARs in Neuroinflammation
Editorial
Author Information
Author(s): Michael K. Racke, Paul D. Drew
Conclusion
Modulation of PPARs may be effective in treating neuroinflammatory diseases.
Supporting Evidence
- Activated peripheral immune cells can enter and function within the CNS.
- Chronically activated microglia can produce toxic molecules leading to neurodegeneration.
- PPAR agonists inhibit the production of proinflammatory molecules by immune cells.
Takeaway
This article talks about how certain molecules can help reduce inflammation in the brain, which is important for treating diseases like Alzheimer's.
Digital Object Identifier (DOI)
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