Chronic granulomatous disease: a review of the infectious and inflammatory complications
2011
Chronic Granulomatous Disease: A Review of Complications
publication
Evidence: moderate
Author Information
Author(s): Song EunKyung, Jaishankar Gayatri Bala, Saleh Hana, Jithpratuck Warit, Sahni Ryan, Krishnaswamy Guha
Primary Institution: East Tennessee State University
Conclusion
Chronic Granulomatous Disease (CGD) leads to severe recurrent infections and inflammatory complications due to defective phagocyte function.
Supporting Evidence
- CGD is characterized by repeated infections with bacterial and fungal pathogens.
- Major advances have occurred in the diagnosis and treatment of CGD.
- Defects in phagocyte function lead to significant morbidity and mortality.
Takeaway
Chronic Granulomatous Disease makes it hard for the body to fight off germs, causing lots of infections and inflammation.
Digital Object Identifier (DOI)
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