Case Report on Creutzfeldt-Jacob Disease
Author Information
Author(s): Gozke Eren, Erdal Nursel, Unal Muge
Primary Institution: FSM Teaching and Research Hospital, Istanbul, Turkey
Hypothesis
Can diffusion weighted MRI improve the diagnosis of Creutzfeldt-Jacob Disease?
Conclusion
Cortical ribboning observed in diffusion weighted MRI is a useful diagnostic sign for Creutzfeldt-Jacob Disease.
Supporting Evidence
- EEG showed periodic triphasic waves in the patient.
- Hyperintense signal changes in cortical regions were observed in DW MRI.
- Protein 14-3-3 was detected in the cerebrospinal fluid.
Takeaway
This study talks about a 70-year-old man who had a rare brain disease called Creutzfeldt-Jacob Disease, and how special brain scans helped doctors figure out what was wrong.
Methodology
The diagnosis was established based on medical history, clinical presentation, findings of diffusion weighted MRI, EEG, and CSF.
Limitations
The study is based on a single case report, which may not be generalizable.
Participant Demographics
One 70-year-old male patient.
Digital Object Identifier (DOI)
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