The prevalence of canine Leishmania infantum infection in Sichuan Province, southwestern China detected by real time PCR
2011

Prevalence of Canine Leishmania Infection in Sichuan, China

Sample size: 314 publication 10 minutes Evidence: moderate

Author Information

Author(s): Shang Li-min, Peng Wei-ping, Jin Hong-tao, Xu Ding, Zhong Ni-na, Wang Wen-long, Wu You-xi, Liu Quan

Primary Institution: Institute of Military Veterinary, Academy of Military Medical Sciences

Hypothesis

What is the prevalence of Leishmania DNA in dogs from Sichuan Province, China?

Conclusion

L. infantum infection in dogs is widespread in Sichuan Province, which poses a public health risk due to its potential transmission to humans.

Supporting Evidence

  • The overall prevalence of Leishmania DNA in dogs was 24.8%.
  • The positive rate was 23.5% in Wenchuan County, 28.2% in Heishui County, and 24.1% in Jiuzhaigou County.
  • Older and symptomatic dogs had a higher prevalence of infection.

Takeaway

Infected dogs in Sichuan can spread a disease to humans, so it's important to check and treat these dogs.

Methodology

Real-time PCR was used to detect Leishmania DNA in blood samples from dogs.

Potential Biases

Potential bias in sample selection as only household dogs were included.

Limitations

The study may not represent all dogs in the region as it was limited to specific counties.

Participant Demographics

Dogs from Wenchuan, Heishui, and Jiuzhaigou Counties in Sichuan Province.

Statistical Information

P-Value

0.001

Confidence Interval

1.4-4.2

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1756-3305-4-173

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