The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States
2011

The Burden of Fibromyalgia in the US

Sample size: 203 publication 10 minutes Evidence: high

Author Information

Author(s): Caroline Schaefer, Arthi Chandran, Meghan Hufstader, Rebecca Baik, Michael McNett, Don Goldenberg, Robert Gerwin, Gergana Zlateva

Primary Institution: Covance Market Access Services Inc.

Hypothesis

How does the severity of fibromyalgia impact patients' symptoms, quality of life, and productivity?

Conclusion

Fibromyalgia imposes a substantial humanistic burden on patients in the United States, leading to significant productivity loss, especially among those with more severe symptoms.

Supporting Evidence

  • 92% of subjects were prescribed medication for fibromyalgia.
  • 50% of subjects reported some disruption in their employment due to fibromyalgia.
  • Subjects with worse fibromyalgia severity reported significantly increased pain severity, fatigue, and sleep disturbance.

Takeaway

Fibromyalgia makes people feel a lot of pain and tiredness, which can make it hard for them to work and enjoy life. The worse the fibromyalgia, the harder it is for them.

Methodology

This cross-sectional observational study recruited 203 fibromyalgia patients from 20 physician offices and assessed their symptoms and quality of life using various questionnaires.

Potential Biases

Potential bias due to voluntary participation of practices and the requirement for patients to have experienced pain in the past 24 hours.

Limitations

The study may not be generalizable to all fibromyalgia patients as it only included those actively seeking care and may have biased the sample towards more severe cases.

Participant Demographics

Mean age was 47.9 years, with 95% female participants.

Statistical Information

P-Value

p<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/1477-7525-9-71

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