Extramedullary Myeloma in an HIV-Positive Patient
Author Information
Author(s): Feller Liviu, White Jason, Wood Neil H, Bouckaert Michael, Lemmer Johan, Raubenheimer Erich J
Primary Institution: University of Limpopo, Pretoria, South Africa
Hypothesis
How does HIV status affect the clinical presentation and progression of myeloma?
Conclusion
The case illustrates that myeloma can present aggressively in HIV-positive patients and may indicate undiagnosed HIV infection.
Supporting Evidence
- The patient had a large facial swelling and proptosis of the left eye.
- Microscopic examination confirmed a neoplastic plasma cell tumor.
- Serum protein electrophoresis showed elevated IgG kappa monoclonal protein.
- The patient was HIV-seropositive with a very low CD4+ T cell count.
Takeaway
This study is about a woman with a serious type of cancer called myeloma, which was found because of a big swelling in her face, and she also had HIV.
Methodology
Case report detailing clinical presentation, diagnostic procedures, and findings.
Limitations
The clonality of the plasma cell population could not be determined due to the lack of a trephine biopsy.
Participant Demographics
48-year-old black female.
Digital Object Identifier (DOI)
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