Multifocal Gastric GISTs with Lymph Node Metastases in Young Patients
Author Information
Author(s): Claudia Otto, Abbas Agaimy, Alexander Braun, Jochen Rädecke, Jens Hoeppner, Gerald Illerhaus, Martin Werner, Udo Kontny, Florian Haller
Primary Institution: University Hospital Freiburg, Germany
Hypothesis
Pediatric gastrointestinal stromal tumors (GISTs) may represent an early manifestation or forme fruste of the Carney triad.
Conclusion
Pediatric GISTs show characteristics similar to those of the Carney triad, except for the absence of other triad components.
Supporting Evidence
- Pediatric GISTs are rare, representing only 1-2% of all GIST cases.
- Carney triad is a rare condition with approximately 120 cases reported worldwide.
- Both pediatric and CT-GISTs frequently metastasize to regional lymph nodes.
Takeaway
This study looks at three young patients with stomach tumors that spread to lymph nodes, showing they might be linked to a rare condition called Carney triad.
Methodology
The study compares clinical and histomorphological features of three cases of multifocal gastric GISTs in young patients.
Limitations
The study is based on a small sample size of three cases.
Participant Demographics
Three patients: two females aged 15 and 13, and one female aged 40.
Digital Object Identifier (DOI)
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