Case Report of Suspected Idiopathic Sclerosing Orbital Inflammation
Author Information
Author(s): Nagai Kazuki, Andoh Kazuo, Nakamura Noriko, Sakata Katsumi
Primary Institution: Nagai Clinic, Saiseikai Yokohama-shi Nanbu Hospital, Yokohama City University
Hypothesis
Is idiopathic sclerosing orbital inflammation related to immunoglobulin G4-related disease?
Conclusion
The case suggests that idiopathic sclerosing orbital inflammation may be associated with elevated serum immunoglobulin G4 levels.
Supporting Evidence
- The patient's serum IgG4 levels were significantly elevated.
- Symptoms improved after treatment with oral prednisolone.
- Imaging studies indicated infiltration of fibrotic tissues in the orbit.
Takeaway
This study is about an 82-year-old woman with eye swelling and drooping, which was linked to a rare condition that might be related to a specific type of immune response.
Methodology
The patient was treated with oral prednisolone, and her symptoms and serum IgG4 levels were monitored over time.
Limitations
A biopsy could not be performed due to lack of patient consent, limiting definitive diagnosis.
Participant Demographics
An 82-year-old Japanese woman with a history of chronic thyroiditis.
Digital Object Identifier (DOI)
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