Fast synthesis of 1,3-DAG by Lecitase® Ultra-catalyzed esterification in solvent-free system
2011

Fast Synthesis of 1,3-DAG Using Lecitase® Ultra

publication Evidence: moderate

Author Information

Author(s): Liu Ning, Wang Yong, Zhao Qiangzhong, Zhang Qingli, Zhao Mouming

Primary Institution: South China University of Technology

Hypothesis

Can Lecitase® Ultra effectively catalyze the direct esterification of glycerol with oleic acid in a solvent-free system to produce 1,3-DAG?

Conclusion

Lecitase® Ultra can rapidly synthesize 1,3-DAG in a solvent-free system with high efficiency and yield.

Supporting Evidence

  • The optimal conditions for producing 1,3-DAG were identified as a mole ratio of 1:5 for oleic acid to glycerol, a temperature of 40°C, and a reaction time of 1.5 hours.
  • The esterification efficiency reached 80.3% and the 1,3-DAG content was 54.8% under optimal conditions.
  • The study demonstrated that a solvent-free system significantly improved the esterification efficiency compared to traditional organic solvent methods.
  • Recycling of the enzyme was shown to be effective, maintaining a high level of 1,3-DAG content over multiple runs.

Takeaway

This study shows that a special enzyme can help make a type of oil quickly and without using any harmful solvents.

Methodology

The study involved using Lecitase® Ultra to catalyze the esterification of glycerol and oleic acid under various conditions, including mole ratio, temperature, and enzyme load.

Limitations

The study did not explore the long-term stability of the enzyme or the economic feasibility of the process at a larger scale.

Digital Object Identifier (DOI)

10.1002/ejlt.201000507

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