Thyroid-stimulating hormone elevation misdiagnosed as subclinical hypothyroidism following non-convulsive status epilepticus: a case report
2011

Misdiagnosis of Thyroid Issues After Seizures

Sample size: 1 publication Evidence: low

Author Information

Author(s): Wada Akira, Suzuki Yoshiaki, Midorikawa Sanae, Takeuchi Satoshi, Kunii Yasuto, Yabe Hirooki, Niwa Shin-Ichi

Primary Institution: Fukushima Medical University School of Medicine

Hypothesis

Can non-convulsive status epilepticus cause thyroid-stimulating hormone elevation that is misdiagnosed as subclinical hypothyroidism?

Conclusion

The study suggests that TSH elevation following non-convulsive status epilepticus can be misdiagnosed as subclinical hypothyroidism, leading to inappropriate treatment.

Supporting Evidence

  • The patient had elevated TSH levels but normal fT3 and fT4 levels.
  • She was misdiagnosed and treated with levothyroxine, which induced further seizures.
  • Endocrine tests showed no evidence of thyroid disorder after episodes of NCSE.

Takeaway

A woman had high thyroid hormone levels after a seizure, but doctors thought she had a thyroid problem and gave her medicine that made her seizures worse.

Methodology

Case report detailing the patient's medical history, symptoms, and treatment.

Potential Biases

Potential bias in diagnosis due to the rarity of non-convulsive status epilepticus.

Limitations

The findings are based on a single case report, limiting generalizability.

Participant Demographics

68-year-old Japanese woman.

Digital Object Identifier (DOI)

10.1186/1752-1947-5-432

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