Central Corneal Thickness and Intraocular Pressure in Malay Children
Author Information
Author(s): Heidary Fatemah, Gharebaghi Reza, Wan Hitam Wan Hazabbah, Naing Nyi Nyi, Wan-Arfah Nadiah, Shatriah Ismail
Primary Institution: Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia
Hypothesis
To determine the mean values for central corneal thickness (CCT) and intraocular pressure (IOP) and the relationship between these values in healthy Malay children.
Conclusion
CCT and IOP are strongly related in healthy Malay children aged 8 to 16, with the mean CCT being lower than that of children from other ethnic groups.
Supporting Evidence
- The mean CCT was found to be 530.87±30.79 µm.
- The mean IOP was found to be 15.65±3.05 mm Hg.
- CCT did not vary with age.
- For every 100-µm increase in CCT, IOP increased by 3.5 mm Hg.
Takeaway
This study looked at how thick the corneas are and the pressure inside the eyes of Malay children, finding that thicker corneas mean higher eye pressure.
Methodology
A cross-sectional study measuring CCT and IOP in 54 healthy Malay children using specular microscopy and non-contact air-puff tonometry.
Potential Biases
Potential bias due to self-reported ethnicity and exclusion of children with ocular abnormalities.
Limitations
The study's cross-sectional nature and small sample size limit the ability to infer long-term relationships.
Participant Demographics
54 Malay children aged 8 to 16, with 28 boys and 26 girls.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI 0.02, 0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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