Coordinations between gene modules control the operation of plant amino acid metabolic networks
2009

Gene Coordination in Plant Amino Acid Metabolism

Sample size: 211 publication Evidence: moderate

Author Information

Author(s): Hadar Less, Gad Galili

Primary Institution: Weizmann Institute of Science

Hypothesis

The study hypothesizes that specific groups of highly coordinated genes regulate branched amino acid metabolic networks in plants in response to environmental stresses.

Conclusion

The study concludes that branched amino acid metabolic networks in plants are regulated by specific groups of highly coordinated genes that enable necessary metabolic adjustments for stress adaptation.

Supporting Evidence

  • The study identified two oppositely regulated groups of highly coordinated genes within the Asp-family and aromatic amino acid metabolic networks.
  • These genes showed adjustable expression responses to various stress cues.
  • The findings suggest that these genes are central to regulating metabolic shifts in response to environmental changes.

Takeaway

Plants have special genes that help them change how they make amino acids when they face stress, like drought or pests.

Methodology

The study used a novel bioinformatics approach called 'Gene Coordination' to analyze publicly available microarray data from Arabidopsis plants.

Limitations

The study focuses on short-term responses and may not capture long-term adaptations in metabolic networks.

Participant Demographics

The study primarily involved Arabidopsis plants.

Digital Object Identifier (DOI)

10.1186/1752-0509-3-14

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