Contribution of problem drug users’ deaths to excess mortality in Scotland: secondary analysis of cohort study
2008

Impact of Drug Use on Mortality in Scotland

Sample size: 1033 publication 10 minutes Evidence: high

Author Information

Author(s): Michael Bloor, Maria Gannon, Gordon Hay, Graham Jackson, Alastair H Leyland, Neil McKeganey

Primary Institution: Centre for Drug Misuse Research, University of Glasgow

Hypothesis

Is the higher mortality rate in Scotland compared to England explained by problem drug use?

Conclusion

Problem drug use significantly contributes to excess mortality in Scotland, accounting for about a third of the difference compared to England.

Supporting Evidence

  • 38 deaths occurred in the cohort, with a standardised mortality ratio of 1244.
  • 32.0% of the excess mortality in Scotland is due to drug use.
  • Only 22 of the 38 deaths were classified as drug related.

Takeaway

In Scotland, many people who use drugs die, and this is a big reason why more people die there compared to England.

Methodology

Secondary analysis of the DORIS cohort study involving drug users in Scotland.

Potential Biases

Potential numerator-denominator bias due to differences in definitions of drug users.

Limitations

The study relies on mortality data that may not fully capture all drug-related deaths due to varying definitions.

Participant Demographics

Mean age of participants was 28, with 69% being male.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% credible interval 876 to 1678

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1136/bmj.a478

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication