Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases
2012
Understanding Postprandial Inflammation and Its Relationship to Lifestyle Behaviour and Metabolic Diseases
publication
Evidence: moderate
Author Information
Author(s): Boudewijn Klop, Spencer D. Proctor, John C. Mamo, Kathleen M. Botham, Manuel Castro Cabezas
Hypothesis
The study investigates the relationship between postprandial lipemia, inflammation, vascular function, and lifestyle behaviors.
Conclusion
Postprandial hyperlipidemia is linked to increased cardiovascular risk, but lifestyle changes can help mitigate this risk.
Supporting Evidence
- Postprandial lipemia is prevalent during conditions of obesity and insulin resistance.
- Statins can reduce postprandial lipemia but do not sufficiently lower triglycerides in hypertriglyceridemic conditions.
- Lifestyle interventions like diet and exercise can effectively reduce postprandial lipemia.
- Postprandial hyperlipidemia is linked to increased cardiovascular risk.
- Chylomicron remnants can penetrate arterial walls and contribute to atherosclerosis.
Takeaway
After eating, our bodies can have too much fat in the blood, which can hurt our hearts, but eating better and exercising can help.
Limitations
The study does not provide definitive evidence on whether lowering postprandial lipemia directly reduces cardiovascular disease risk.
Digital Object Identifier (DOI)
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