Esmolol's Effect on Heart Recovery After Surgery
Author Information
Author(s): Sun Jie, Ding Zhengnian, Qian Yanning
Primary Institution: Dept. of Anesthesiology, the first affiliated hospital with Nanjing Medical University
Hypothesis
Does esmolol improve cardiac recovery and rhythm during cardiac surgeries?
Conclusion
Esmolol has a positive effect on cardiac recovery in cardiopulmonary bypass surgeries.
Supporting Evidence
- Esmolol treatment increased the auto re-beat success rate.
- Esmolol reduced the incidence of ventricular fibrillation after primary re-beat.
- Esmolol decreased the need for vasoactive drugs during weaning from bypass.
Takeaway
Esmolol helps the heart recover better after surgery by making it beat normally again and reducing dangerous heart rhythms.
Methodology
60 patients were randomly assigned to receive esmolol or saline before surgery, and various cardiac recovery metrics were measured.
Limitations
Two patients were excluded due to cardiopericarditis, which may affect the generalizability of the results.
Participant Demographics
Patients with rheumatic heart disease undergoing elective single mitral valve replacements.
Statistical Information
P-Value
p<0.001 for auto re-beat ratio, p=0.005 for ventricular fibrillation, p=0.014 for vasoactive drug use
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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