Analysis of the genomic homologous recombination in Theilovirus based on complete genomes
2011

Genomic Recombination in Theilovirus

Sample size: 21 publication Evidence: moderate

Author Information

Author(s): Sun Guangming, Zhang Xiaodan, Yi Maoli, Shao Shihe, Zhang Wen

Primary Institution: The Fourth Affiliated Hospital of Jiangsu University

Hypothesis

How does genomic recombination occur in Theilovirus?

Conclusion

The study identified seven significant recombination events in Theilovirus, with some potentially occurring non-naturally.

Supporting Evidence

  • Seven potentially significant recombination events were identified.
  • Four of the recombination events might happen non-naturally.
  • Phylogenetic analysis showed two major genetic groups of Theilovirus.

Takeaway

Scientists looked at the genes of a virus called Theilovirus and found that it can mix its genes in interesting ways, which might help it change over time.

Methodology

Phylogenetic and recombination analysis of complete Theilovirus genomes from GenBank.

Potential Biases

Potential sequencing errors or contamination could affect the results of some recombination events.

Limitations

Some recombination events may have occurred non-naturally due to lab conditions.

Statistical Information

P-Value

1.3 × 10^-4

Statistical Significance

p ≤ 1.3 × 10^-4

Digital Object Identifier (DOI)

10.1186/1743-422X-8-439

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