Predictors of Extubation Success in Patients with Middle Cerebral Artery Acute Ischemic Stroke
2011

Predictors of Extubation Success in Stroke Patients

Sample size: 71 publication Evidence: moderate

Author Information

Author(s): Wendell Linda C., Raser Jonathan, Kasner Scott, Park Soojin

Primary Institution: Hospital of the University of Pennsylvania

Hypothesis

Patients with middle cerebral artery (MCA) acute ischemic stroke (AIS) might have specific predictors of successful extubation.

Conclusion

The Glasgow Coma Scale (GCS) score may be an important predictor of successful extubation in MCA AIS patients.

Supporting Evidence

  • Thirty-seven patients (79%) were successfully extubated, while 10 patients (21%) failed extubation.
  • Patients with a GCS score ≥8T trended toward extubating successfully.
  • Higher median extubation GCS scores were observed in those who successfully extubated compared to those who failed.

Takeaway

Doctors can use a score called the Glasgow Coma Scale to help decide if stroke patients can safely breathe on their own after being on a ventilator.

Methodology

Retrospective cohort study of MCA AIS patients requiring intubation.

Potential Biases

Potential practitioner bias in extubation decisions due to lack of standardized protocols.

Limitations

The study is limited by its retrospective design and small sample size from a single institution.

Participant Demographics

Patients included had MCA AIS, with a mix of genders and ages, and various medical histories.

Statistical Information

P-Value

0.047

Confidence Interval

0.94–580.27

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4061/2011/248789

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