Infliximab for Treating Kawasaki Disease
Author Information
Author(s): Brogan Robert J, Eleftheriou Despina, Gnanapragasam James, Klein Nigel J, Brogan Paul A
Primary Institution: UCL Institute of Child Health and Great Ormond Street Hospital
Hypothesis
Can infliximab effectively treat intravenous immunoglobulin resistant Kawasaki disease complicated by coronary artery aneurysms?
Conclusion
Infliximab was successful in treating an 8-year-old boy with IVIG resistant Kawasaki disease and severe coronary artery aneurysms.
Supporting Evidence
- The patient had severe coronary artery aneurysms and ongoing inflammation despite standard treatments.
- Infliximab was administered after the patient did not respond to two doses of IVIG.
- Following infliximab treatment, the patient's fever and arthritis subsided within 24 hours.
Takeaway
A boy with a serious heart condition got better after receiving a special medicine called infliximab when other treatments didn't work.
Methodology
Case report detailing the treatment of a single patient with infliximab after failure of standard treatments.
Limitations
This is a single case report, limiting the generalizability of the findings.
Participant Demographics
An 8-year-old male patient.
Digital Object Identifier (DOI)
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