A historically controlled, single-arm, multi-centre, prospective trial to evaluate the safety and efficacy of MonoMax® suture material for abdominal wall closure after primary midline laparotomy.
2008

Study on MonoMax® Suture Material for Abdominal Surgery

Sample size: 150 publication

Author Information

Author(s): Fischer Lars, Baumann Petra, Hüsing Johannes, Seidlmayer Christoph, Albertsmeier Markus, Franck Annette, Luntz Steffen, Seiler Christoph M, Knaebel Hanns-Peter

Primary Institution: University of Heidelberg, Germany

Hypothesis

The frequency of wound infection and of re-operation due to burst abdomen until day of discharge are equal or lower in the patient cohort enrolled in the ISSAAC-Trial compared to patients included in the INSECT-Trial.

Conclusion

The ISSAAC trial aims to assess whether the use of an ultra-long-lasting absorbable monofilament suture material is safe and efficient.

Supporting Evidence

  • The incidence of incisional hernias after midline laparotomy remains high, ranging from 9% to 20%.
  • 52% of incisional hernias occur within 6 months postoperatively.
  • The study aims to find out whether the use of MonoMax® will reduce the rate of wound infections.

Takeaway

This study is testing a new type of suture to see if it helps prevent complications after surgery on the belly.

Methodology

A historically controlled, single-arm, multi-centre, prospective trial evaluating the safety and efficacy of MonoMax® suture material in 150 patients.

Digital Object Identifier (DOI)

10.1186/1471-2482-8-12

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