Parental Chronic Disease and PCOS in Daughters
Author Information
Author(s): Michael J. Davies, Jennifer L. Marino, Kristyn J. Willson, Wendy A. March, Vivienne M. Moore
Primary Institution: The University of Adelaide
Hypothesis
Are parents of young women with PCOS more likely to have a history of diabetes or cardiovascular disease?
Conclusion
Mothers and fathers of women with PCOS are more likely to have cardiovascular diseases compared to parents of women without PCOS.
Supporting Evidence
- Mothers of women with PCOS were more likely to have cardiovascular disease (RR 1.78).
- Fathers of women with PCOS were more than twice as likely to have heart disease (RR 2.36).
- Fathers of women with PCOS were over four times as likely to have had a stroke (RR 4.37).
Takeaway
If a woman has polycystic ovary syndrome (PCOS), her parents are more likely to have heart problems or diabetes.
Methodology
Structured interviews were conducted with participants about their medical history and that of their parents.
Potential Biases
Potential reporting bias due to reliance on participant recollection of parental health.
Limitations
The study relied on participant reports of parental disease history, which may introduce recall bias.
Participant Demographics
Participants were women born in Adelaide between 1973 and 1975, with a focus on those diagnosed with PCOS.
Statistical Information
P-Value
<0.05
Confidence Interval
95% CI 1.29, 2.47
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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