Does the radiofrequency impedance-controlled endometrial ablation have any morphologic effects on uterine leiomyomata?: Report of 3 cases
2008

Effects of NovaSure Endometrial Ablation on Uterine Tumors

Sample size: 3 publication Evidence: low

Author Information

Author(s): Fadare Oluwole, Wang Sa, Renshaw Idris L

Primary Institution: Wilford Hall Medical Center

Hypothesis

Does the radiofrequency impedance-controlled endometrial ablation have any morphologic effects on uterine leiomyomata?

Conclusion

The study found no significant histologic changes in leiomyomata after NovaSure endometrial ablation.

Supporting Evidence

  • All three cases showed typical morphologic features of benign smooth muscle neoplasms.
  • None of the leiomyomata displayed any necrosis or evidence of degeneration.
  • The average mitotic index for the three cases was 0.4 per 50 high power fields.

Takeaway

Doctors looked at three patients' uterine tumors after a special treatment and found that the treatment didn't change the tumors at all.

Methodology

Three uteri with leiomyomatous mass lesions were evaluated for histologic changes after NovaSure endometrial ablation.

Limitations

The study only included three cases, which may not represent a broader population.

Participant Demographics

Two patients were Caucasian and one was African-American, aged 45 to 51.

Digital Object Identifier (DOI)

10.1186/1746-1596-3-28

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