A prospective cohort study of neighborhood stress and ischemic heart disease in Japan: a multilevel analysis using the JACC study data
2011

Neighborhood Stress and Heart Disease in Japan

Sample size: 110792 publication Evidence: moderate

Author Information

Author(s): Fujino Yoshihisa, Tanabe Naohito, Honjo Kaori, Suzuki Sadao, Shirai Kokoro, Iso Hiroyasu, Tamakoshi Akiko

Primary Institution: University of Occupational and Environmental Health

Hypothesis

Does area-level stress affect the likelihood of death due to ischemic heart disease?

Conclusion

Area-level stress affects the likelihood of death due to ischemic heart disease in men.

Supporting Evidence

  • The study followed participants for 15 years, recording 936 deaths due to ischemic heart disease.
  • Area-level stress was calculated based on self-reported stress levels from residents.
  • Mortality rate ratios indicated a significant association between area-level stress and heart disease mortality in men.

Takeaway

Living in a stressful neighborhood can make people more likely to die from heart problems, especially men.

Methodology

The study used multilevel Poisson regression models to analyze data from a cohort of 110,792 residents across 45 areas in Japan.

Potential Biases

Potential bias due to self-reported data and unmeasured confounding factors.

Limitations

Residual confounding may be present, and the validity of self-reported stress measures was not evaluated.

Participant Demographics

Participants were aged 40-79 years, with 32,183 men and 45,896 women included in the analysis.

Statistical Information

P-Value

0.043

Confidence Interval

1.00-1.12

Statistical Significance

p=0.043

Digital Object Identifier (DOI)

10.1186/1471-2458-11-398

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication