Automated Analysis of Water-Soluble Vitamins in Tablets
Author Information
Author(s): S. C. Coverly
Primary Institution: Technicon Instruments Company Ltd
Hypothesis
The efficiency of high-performance liquid chromatography (HPLC) can be improved with automated sample preparation techniques.
Conclusion
A fully automated method for analyzing water-soluble vitamins in tablets and capsules has been developed, increasing analysis rate and reducing errors.
Supporting Evidence
- The system can analyze five to 10 samples per hour.
- Linearity, recovery, and reproducibility are similar to previously reported manual LC methods.
- The day-to-day precision for the vitamins was between 1.8% and 5.8%.
Takeaway
This study created a machine that can quickly check how much of certain vitamins are in tablets, making it easier and faster than doing it by hand.
Methodology
The study used a FAST-LC system for automated sample preparation and HPLC analysis of vitamins in various multi-vitamin products.
Limitations
The system was not suitable for veterinary products containing meat and bone meal due to blockage issues.
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