Evaluation of day one embryo quality and IVF outcome – a comparison of two scoring systems
2009

Comparing Two Scoring Systems for Embryo Quality in IVF

Sample size: 364 publication Evidence: moderate

Author Information

Author(s): Jana Brezinova, Ivana Oborna, Magda Svobodova, Helena Fingerova

Primary Institution: Dept. of Obstetrics and Gynaecology, Faculty of Medicine, Palacky University of Olomouc, Olomouc, Czech Republic

Hypothesis

Which embryo scoring system better predicts implantation potential in IVF?

Conclusion

Early cleavage is a better independent marker of implantation potential than zygote morphology.

Supporting Evidence

  • Early cleavage embryos showed significantly higher clinical pregnancy rates compared to non-early cleavage embryos.
  • The best outcomes were achieved when both scoring systems were used together.

Takeaway

This study looked at two ways to score embryos to see which one helps doctors pick the best ones for pregnancy. It found that embryos that start dividing early are more likely to lead to a baby.

Methodology

The study assessed the quality of 2708 embryos from 364 IVF cycles using two scoring systems and analyzed the outcomes of embryo transfers.

Potential Biases

Potential bias in embryo selection and retrospective analysis.

Limitations

The study is retrospective and may be influenced by selection bias.

Participant Demographics

Women under the age of 39 years undergoing IVF.

Statistical Information

P-Value

p = 0.003 and p = 0.006

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1477-7827-7-9

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