Record linked retrospective cohort study of 4.6 million people exploring ethnic variations in disease: myocardial infarction in South Asians
2007

Ethnic Variations in Myocardial Infarction: A Study of South Asians

Sample size: 4600000 publication 10 minutes Evidence: moderate

Author Information

Author(s): Colin Fischbacher, Raj Bhopal, Chris Povey, M Steiner, J Chalmers, Ganka Mueller, Joan Jamieson, David Knowles

Primary Institution: Information Services Division, NHS National Services Scotland

Hypothesis

Can record linkage techniques ethically and effectively demonstrate ethnic variations in disease incidence and outcomes?

Conclusion

The study found that South Asians have a higher incidence of acute myocardial infarction but better survival rates compared to non-South Asians.

Supporting Evidence

  • 94% of census records were matched to health records.
  • South Asians had a higher incidence rate of AMI compared to non-South Asians.
  • Survival rates after AMI were better for South Asians than for non-South Asians.

Takeaway

This study looked at heart attacks in South Asians and found they have more heart attacks but survive them better than other groups.

Methodology

The study used probability matching to link census data with hospital discharge and mortality records.

Potential Biases

Potential bias due to lower linkage rates for South Asians compared to non-South Asians.

Limitations

The study did not separate different South Asian ethnic groups due to low numbers.

Participant Demographics

Participants included South Asians (Pakistani, Indian, Bangladeshi) and non-South Asians in Scotland.

Statistical Information

P-Value

0.43 for death by 30 days following AMI for South Asians compared to non-South Asians.

Confidence Interval

95% CI 1.17, 1.78 for incidence rate ratio; 95% CI 0.43, 0.81 for hazard ratio.

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2458-7-142

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