Wound Healing Effects of Rubus sanctus
Author Information
Author(s): Süntar Ipek, Koca Ufuk, Keleş Hikmet, Akkol Esra Küpeli
Primary Institution: Gazi University
Hypothesis
The study aims to evaluate the wound healing activity of Rubus sanctus using various extracts in animal models.
Conclusion
The methanolic extract of Rubus sanctus significantly promotes wound healing in animal models.
Supporting Evidence
- The methanolic extract showed 80.6% wound contraction by day 12.
- The tensile strength of wounds treated with the methanolic extract was significantly higher than other groups.
- Histopathological examination showed better re-epithelization in the methanol extract group.
Takeaway
This study shows that a plant called Rubus sanctus can help heal wounds better than some other treatments.
Methodology
The study used incision and excision wound models on rats and mice to test the effects of different extracts of Rubus sanctus.
Limitations
The study was conducted only in animal models, and further research is needed to confirm results in humans.
Participant Demographics
Male Sprague-Dawley rats and Swiss albino mice were used in the study.
Statistical Information
P-Value
p ≤ 0.001
Statistical Significance
p ≤ 0.001
Digital Object Identifier (DOI)
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