Case Report of Metastatic Gallbladder Adenocarcinoma with Signet-Ring Cells
Author Information
Author(s): Bazan Fernando, Sanchez Juan, Aguilar Guadalupe, Radosevic Aleksandar, Busto Marcos, Zuccarino Flavio, Pijuan Lara, Risueño Noelia
Primary Institution: Parc de Salut Mar Hospital, Barcelona, Cataluña, Spain
Conclusion
The proliferation of signet-ring cells in a gallbladder adenocarcinoma worsens the prognosis of an already adverse neoplasm.
Supporting Evidence
- Signet-ring cell carcinoma is a rare and aggressive variant of mucinous adenocarcinoma.
- The patient presented with multiple metastases in various organs after initial surgery.
- Histology revealed poorly differentiated adenocarcinoma with signet-ring cells.
Takeaway
A 63-year-old man had a rare type of gallbladder cancer that spread quickly, and he refused chemotherapy, which led to a poor outcome.
Methodology
The case involved a 63-year-old man diagnosed with gallbladder signet-ring cell adenocarcinoma after an elective cholecystectomy, followed by imaging and cytology to assess metastasis.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
63-year-old Arab man.
Digital Object Identifier (DOI)
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