Managing Elderly Breast Cancer Patients Without Radiotherapy
Author Information
Author(s): Valassiadou Kalliope, Morgan David AL, Robertson John FR, Pinder Sarah E, Cheung Kwok-Leung
Primary Institution: Nottingham City Hospital
Hypothesis
Is breast conserving surgery without adjuvant radiotherapy effective for elderly patients with breast cancer?
Conclusion
Omitting radiotherapy after successful breast conserving surgery in elderly patients with ER positive tumors receiving tamoxifen may be acceptable.
Supporting Evidence
- The local recurrence rate in the no RT group was 8.4%.
- In the ER positive group, the local recurrence rate was 0.92% per annum.
- Breast cancer specific survival was correlated to histological grade and ER status.
Takeaway
Older women with breast cancer might not need radiation after surgery if they take a medicine called tamoxifen.
Methodology
A retrospective review of 92 elderly patients who underwent breast conserving surgery for invasive carcinoma.
Potential Biases
Potential selection bias due to the retrospective nature of the study.
Limitations
The study is retrospective and may not account for all variables affecting outcomes.
Participant Demographics
Elderly patients, median age 75 years, range 70-87 years.
Statistical Information
P-Value
0.024
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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