Efficacy and Safety of Human Placental Extract Solution on Fatigue: A Double-Blind, Randomized, Placebo-Controlled Study
2012

Effect of Human Placental Extract on Fatigue

Sample size: 315 publication Evidence: moderate

Author Information

Author(s): Lee Kang-Kon, Choi Whan-Seok, Yum Keun-Sang, Song Sang-Wook, Ock Sun-Myeong, Park Sat-Byul, Kim Moon-Jong

Primary Institution: The Catholic University of Korea School of Medicine

Hypothesis

The human placental extract solution is effective in improving fatigue.

Conclusion

The human placental extract solution was effective in the improvement of fatigue.

Supporting Evidence

  • The fatigue recovery rate was 71.00% in the group receiving the Unicenta solution.
  • The fatigue recovery rate was 71.72% in the group receiving exclusively human placental extract.
  • The placebo group had a fatigue recovery rate of 44.21%.
  • Statistically significant differences were found between the experimental groups and the placebo group.

Takeaway

This study tested a special liquid made from human placenta to see if it helps people feel less tired, and it worked well.

Methodology

A double-blind, randomized, placebo-controlled study with 315 subjects assigned to three groups receiving different treatments over four weeks.

Potential Biases

Potential bias due to high expectations from participants regarding the treatment.

Limitations

The study duration was short, and the placebo group showed a higher than expected fatigue recovery rate.

Participant Demographics

Subjects aged 18-75 with persistent fatigue; 87% female.

Statistical Information

P-Value

0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1155/2012/130875

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