HOX Genes in Ovarian Cancer
Author Information
Author(s): Kelly Zoë L, Michael Agnieszka, Butler-Manuel Simon, Pandha Hardev S, Morgan Richard GL
Primary Institution: University of Surrey
Hypothesis
HOX genes play a role in the oncogenesis of ovarian cancer.
Conclusion
HOX genes are involved in ovarian cancer development and may serve as potential diagnostic and therapeutic targets.
Supporting Evidence
- HOX genes are strongly expressed in ovarian cancer.
- Specific HOX gene expression can determine cancer cell identity.
- HOX genes may serve as prognostic and diagnostic markers.
- Altered HOX gene expression is linked to ovarian cancer progression.
Takeaway
HOX genes help determine how ovarian cancer cells behave, and scientists think they could be used to help diagnose and treat the disease.
Methodology
A literature search was performed using terms related to HOX genes and ovarian cancer, with studies accessed through various databases.
Limitations
The review is based on existing literature, which may have varying methodologies and sample sizes.
Statistical Information
P-Value
0.029
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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