Hepatitis C Virus Infection and Its Effects on Liver Health
Author Information
Author(s): Clément Sophie, Pascarella Stéphanie, Negro Francesco
Primary Institution: Division of Clinical Pathology, University Hospitals, Geneva, Switzerland
Hypothesis
HCV infection contributes to the development of steatosis, insulin resistance, and oxidative stress in the liver.
Conclusion
HCV infection is linked to increased oxidative stress and insulin resistance, which can accelerate liver disease progression.
Supporting Evidence
- HCV infection is common, with an average worldwide prevalence of 3%.
- Chronic hepatitis C can lead to cirrhosis and hepatocellular carcinoma.
- Oxidative stress and insulin resistance contribute to steatosis in chronic hepatitis C patients.
Takeaway
Hepatitis C can make your liver sick by causing fat buildup and making it harder for your body to use insulin, which can lead to diabetes.
Methodology
The review discusses various studies and mechanisms linking HCV infection to liver conditions.
Limitations
The review is based on existing literature and may not cover all aspects of HCV's impact on liver health.
Participant Demographics
The study included 42 non-obese, non-diabetic HCV-infected individuals.
Digital Object Identifier (DOI)
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