Electrocardiographic (ECG) criteria for determining left ventricular mass in young healthy men; data from the LARGE Heart study
2009

ECG Criteria for Left Ventricular Mass in Young Men

Sample size: 101 publication 10 minutes Evidence: moderate

Author Information

Author(s): Sohaib Syed M Afzal, Payne John R, Shukla Rajeev, World Michael, Pennell Dudley J, Montgomery Hugh E

Primary Institution: Centre for Cardiovascular Genetics, BHF Laboratories, Royal Free & University College Medical School

Hypothesis

Can ECG criteria accurately identify left ventricular hypertrophy in young healthy men?

Conclusion

ECG criteria for LV hypertrophy may have little value in determining LV mass or the presence of LV hypertrophy in young fit males.

Supporting Evidence

  • 29% of participants had LV hypertrophy as defined by Sokolow-Lyon ECG Amplitude criteria.
  • The study found low sensitivity of ECG criteria in identifying LV hypertrophy in young males.
  • Only Sokolow-Lyon Amplitude and Product showed a significant correlation with indexed LV mass.

Takeaway

This study looked at whether heart tests can tell if young men have a bigger heart muscle. It found that these tests don't work well for young, healthy guys.

Methodology

The study used cardiovascular magnetic resonance (CMR) to measure left ventricular mass and compared it with standard 12-lead ECGs from participants.

Potential Biases

The study only included Caucasian males, which may not represent other demographics.

Limitations

The sample is relatively small, and all subjects are male, which may limit generalizability.

Participant Demographics

101 Caucasian male army recruits with a mean age of 19.7 years.

Statistical Information

P-Value

0.005 for Sokolow-Lyon Amplitude correlation

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1532-429X-11-2

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