RESPONDERS AND NONRESPONDERS WITH KNEE OSTEOARTHRITIS TO TRANSCRANIAL DIRECT CURRENT STIMULATION
2024

Knee Osteoarthritis and Transcranial Direct Current Stimulation

Sample size: 60 publication Evidence: moderate

Author Information

Author(s): Park Juyoung, Tong Heling, Kang Yixin, Miao Hongyu, Ahn Hyochol

Primary Institution: University of Arizona, Florida State University

Hypothesis

The study aims to identify factors that predict response to transcranial direct current stimulation (tDCS) in patients with knee osteoarthritis.

Conclusion

The study found that responders to tDCS had significantly greater reductions in knee pain compared to nonresponders.

Supporting Evidence

  • Responders showed a mean decrease in pain intensity of 34.17, while nonresponders had a decrease of only 2.26.
  • The responder group had higher BMI, height, and weight compared to the nonresponder group.

Takeaway

Some people with knee pain feel better after a special treatment called tDCS, but not everyone does, and we want to find out why.

Methodology

Participants received five 20-minute sessions of active tDCS under supervision.

Limitations

More research is needed to understand the reasons for nonresponse to tDCS.

Participant Demographics

Participants included 41 responders (average age 64.90 years, 41.50% White, 61.00% women) and 19 nonresponders (average age 66.21 years, 47.40% White, 78.90% women).

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0811

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