Treating Bipolar Disorder in Patients on Dialysis: Two Case Reports
Author Information
Author(s): Maneesh Gupta, Srinivas Annadatha
Primary Institution: Lancashire Care NHS Foundation Trust
Hypothesis
How can bipolar disorder be effectively treated in patients undergoing haemodialysis?
Conclusion
The study presents two cases of patients with bipolar disorder and renal failure, highlighting the successful management strategies used.
Supporting Evidence
- Both patients had a diagnosis of bipolar disorder prior to renal failure.
- Valproate was used as a mood stabilizer due to its minimal excretion by the kidneys.
- The first patient showed significant improvement after treatment with valproate and lorazepam.
- The second patient improved after increasing valproate and adding risperidone.
Takeaway
Doctors found ways to help two patients with bipolar disorder who were also on dialysis, using specific medications to make them feel better.
Methodology
Case reports detailing the treatment of two patients with bipolar disorder undergoing haemodialysis.
Potential Biases
Potential bias due to the subjective nature of case reports and lack of control groups.
Limitations
The findings are based on only two case reports, limiting generalizability.
Participant Demographics
Two patients, one male aged 47 and one female aged 44, both with bipolar disorder and renal failure.
Digital Object Identifier (DOI)
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