Herbal Compounds and Toxins Modulating TRP Channels
2008

Herbal Compounds and Toxins Modulating TRP Channels

publication Evidence: moderate

Author Information

Author(s): Vriens Joris, Nilius Bernd, Vennekens Rudi

Primary Institution: KU Leuven

Hypothesis

Many plant compounds interact with specific ion channels and modulate the human body's sensing mechanisms.

Conclusion

This review provides an overview of herbal compounds and toxins that modulate TRP channels, highlighting their potential as therapeutic targets.

Supporting Evidence

  • TRP channels are important for sensing temperature, pain, and other stimuli.
  • Many herbal compounds can activate or inhibit TRP channels, influencing pain perception.
  • Capsaicin and menthol are examples of plant-derived compounds that modulate TRP channels.

Takeaway

Plants have special chemicals that can change how our body feels things like heat and pain, and this study looks at those chemicals.

Methodology

This is a review article summarizing various studies on herbal compounds and their effects on TRP channels.

Limitations

The review does not provide new experimental data but summarizes existing literature.

Digital Object Identifier (DOI)

10.2174/157015908783769644

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