Male Circumcision and Sexually Transmitted Infections
Author Information
Author(s): Sobngwi–Tambekou J, Taljaard D, Nieuwoudt M, Lissouba P, Puren A, Auvert B
Primary Institution: INSERM U687, Hôpital Paul Brousse, Villejuif, France
Hypothesis
Does male circumcision reduce the prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis?
Conclusion
Male circumcision reduces T vaginalis infection among men, which also lowers the risk for women with circumcised partners.
Supporting Evidence
- The study found no protective effect of male circumcision on Neisseria gonorrhoeae.
- There was a borderline association between male circumcision and Chlamydia trachomatis.
- The protective effect of male circumcision on T vaginalis became significant in the as-treated analysis.
Takeaway
Getting circumcised can help men avoid a common infection called Trichomonas, which can also make women sick.
Methodology
Data from a randomized controlled trial in South Africa was analyzed, focusing on urine samples from men aged 18-24.
Potential Biases
Differences in sexual behavior and HIV prevalence between those tested and those not tested may have affected results.
Limitations
Biological samples were not collected throughout the follow-up period, and the study may have introduced bias due to differences between tested and non-tested participants.
Participant Demographics
Men aged 18-24 years, with a mix of ethnic backgrounds.
Statistical Information
P-Value
p=0.030
Confidence Interval
95% CI 0.25 to 0.92
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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