Correlates of preclinical cardiovascular disease in Indigenous and Non-Indigenous Australians: a case control study
2008

Cardiovascular Disease in Indigenous and Non-Indigenous Australians

Sample size: 227 publication Evidence: moderate

Author Information

Author(s): Brian A Haluska, Lionel Chan, Leanne Jeffriess, A Andrew Shaw, Joanne Shaw, Thomas H Marwick

Primary Institution: School of Medicine, University of Queensland, Brisbane, Australia

Hypothesis

Is ethnicity an independent predictor of preclinical cardiovascular disease in Indigenous Australians, independent of risk factors?

Conclusion

Ethnicity is an independent correlate of preclinical cardiovascular disease in Indigenous Australians, even when accounting for known risk factors.

Supporting Evidence

  • Indigenous Australians showed significantly greater carotid intima-media thickness (IMT) compared to non-Indigenous Australians.
  • Cardiovascular risk factors were more prevalent in Indigenous subjects.
  • Age and smoking were independent predictors of IMT.

Takeaway

This study found that Indigenous Australians have a higher risk of heart disease compared to non-Indigenous Australians, even when considering other health issues.

Methodology

The study involved measuring carotid intima-media thickness (IMT) in 227 subjects from different ethnic backgrounds and diabetes statuses.

Potential Biases

Potential bias due to the selection of participants from specific geographic areas.

Limitations

The study may not account for all socio-economic factors influencing cardiovascular health.

Participant Demographics

227 subjects, including 119 Indigenous Australians and 108 Caucasian Australians, aged approximately 50 years.

Statistical Information

P-Value

p<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1476-7120-6-36

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