Depuration of Polybrominated Diphenyl Ethers (PBDEs) and Polychlorinated Biphenyls (PCBs) in Breast Milk from California First-Time Mothers (Primiparae)

2007

Study on Chemical Levels in Breast Milk of First-Time Mothers

Sample size: 18 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hooper Kim, She Jianwen, Sharp Margaret, Chow Joan, Jewell Nicholas, Gephart Rosanne, Holden Arthur

Primary Institution: Environmental Chemistry Laboratory, California Department of Toxic Substances Control

Hypothesis

What are the depuration rates of PBDEs and PCBs in breast milk from first-time mothers during lactation?

Conclusion

Breast-feeding for 6 months reduces PBDE levels by 12-18% and PCB-153 levels by about 4%, but this does not significantly lower the body burden of these chemicals.

Supporting Evidence

PBDE levels decreased 2-3% per month over the first 6 months of breast-feeding.
PCB-153 levels showed more variability, with some mothers experiencing increases.
The study included a total of 18 mothers, providing a more reliable estimate of chemical declines than smaller studies.

Takeaway

Moms who breast-feed don't get rid of harmful chemicals in their milk very quickly, so their babies might still be exposed to these chemicals even after months of nursing.

Methodology

Mothers collected breast milk samples at various intervals, and the levels of PBDEs and PCBs were measured using high-resolution gas chromatography–mass spectrometry.