Geographic Variations in Colorectal Cancer Incidence in Massachusetts
Author Information
Author(s): DeChello Laurie M, Sheehan T Joseph
Primary Institution: Department of Community Medicine and Health Care, University of Connecticut School of Medicine
Hypothesis
Are observed geographic variations in colorectal cancer incidence statistically significant deviations from randomness?
Conclusion
Public health practitioners can use the results of this study to focus their attention onto areas in Massachusetts that need to increase colorectal screening or have elevated risk of colorectal cancer incidence.
Supporting Evidence
- Six geographic areas with significant deviations in colorectal cancer incidence were identified.
- Adjustment for socioeconomic status and urban percentage changed the significance of some areas.
- Public health efforts can be directed to areas with higher incidence rates.
Takeaway
This study looked at where colorectal cancer is more common in Massachusetts and found some areas need more attention for screening.
Methodology
The study used Poisson regression and spatial scan statistics to analyze colorectal cancer cases diagnosed between 1995 and 1998.
Potential Biases
Potential misclassification of cases due to geocoding errors and reliance on Census data.
Limitations
Geocoding errors could misclassify cases, and the use of Census data assumes gradual population changes.
Participant Demographics
The study included 6360 male and 6628 female invasive colorectal cancer cases.
Statistical Information
P-Value
< 0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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