WebScipio: An online tool for the determination of gene structures using protein sequences
2008

WebScipio: A Tool for Gene Structure Prediction from Protein Sequences

Sample size: 280 publication Evidence: moderate

Author Information

Author(s): Odronitz Florian, Pillmann Holger, Keller Oliver, Waack Stephan, Kollmar Martin

Primary Institution: Max-Planck-Institut für Biophysikalische Chemie

Hypothesis

Can WebScipio accurately predict gene structures from protein sequences across various eukaryotic genomes?

Conclusion

WebScipio provides high-quality gene structure predictions that are comparable to manual annotations.

Supporting Evidence

  • WebScipio can predict gene structures for over 250 eukaryotic genomes.
  • The tool's predictions are close to those achieved by manual annotation.
  • WebScipio allows for both in-species and cross-species searches.

Takeaway

WebScipio is a tool that helps scientists find the structure of genes based on protein sequences, making it easier to study different organisms.

Methodology

WebScipio uses a web interface to the Scipio software, allowing users to input protein sequences and retrieve gene structure predictions.

Limitations

The tool's accuracy may vary depending on the quality of the genome data and the phylogenetic distance between species.

Digital Object Identifier (DOI)

10.1186/1471-2164-9-422

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